These types of contraptions only work well on flat, featureless terrain like salt playas. Or on roads. Any hills or uneven terrain with obstructions, and the effort to keep the thing upright and moving forward would exceed the perceived benefit of increased haul capacity. Also, the weight of the cart alone, even if made from ultralight materials, would probably be equivalent to several days of extra food in the pack, which pretty much rules out any resupply distance advantage.
George Meegan, in his book The Longest Walk, used such a cart - he called it a Yoshi cart, named for his Japanese wife, who accompanied him on a mega-walk across the western hemisphere. They followed roads the whole way.
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