Sunshine, you will have a lot more Sunshine and warmer weather if you start in GA and finish in WV, that way the weather will be warming up as you hike along from south to north. You will also have a lot more company on the trail as a lot of NOBO’s will be right in that time slot with you.
If you hike SOBO starting in WV at the end of March, expect to freeze your butts off on the tops of those mountains coming south at that time of year. You will have snow, ice and temps as low at 0 to 10 degrees Fahrenheit at times at this time of year if you SOBO from WV.
Take cold weather gear, lots of food, warm clothes, and crampons if you do it that way.
See you out there. :cheers
Maintain